Cyclerion Therapeutics, INC

Market Movers (8-K)

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NASDAQ
Cyclerion Therapeutics and privately-held Korsana Biosciences announced a definitive merger agreement and a concurrent $380 million private financing to advance Korsana's neurodegenerative disease pipeline, including a lead Alzheimer's program.
Capital raise
Delay expected
NASDAQ
Cyclerion Therapeutics announced positive FDA feedback for its lead product candidate, CYC-126, and formed a Clinical Advisory Board, staying on track for a Phase 2 study in Treatment Resistant Depression.
Capital raise
NASDAQ
Cyclerion Therapeutics announced a strategic collaboration with Medsteer to enhance its anesthetic delivery platform for CYC-126 in treatment-resistant depression, targeting a Phase 2 study in H2 2026.
Capital raise
Worse than expected
NASDAQ
Cyclerion Therapeutics is set to receive a $1.0 million milestone payment from Akebia Therapeutics following the initiation of Phase 2 clinical trials for Praliciguat in focal segmental glomerulosclerosis.
Delay expected
Worse than expected
NASDAQ
Cyclerion Therapeutics has announced a transformational relaunch, securing an exclusive license from MIT to develop therapies for neuropsychiatric disorders, starting with treatment-resistant depression.
Capital raise
NASDAQ
Cyclerion Therapeutics, Inc. announced the results of its Annual Meeting of Shareholders held on June 16, 2025, where all director nominees were re-elected, Ernst & Young LLP was ratified as the independent auditor, and executive compensation was approved.

Quarterly Earnings (10-Q)

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NASDAQ
Cyclerion Therapeutics' Q2 2026 10-Q filing reveals substantial doubt about its ability to continue as a going concern, alongside details of a proposed merger with Korsana Biosciences.
Capital raise
Worse than expected
NASDAQ
Cyclerion Therapeutics reports Q1 2026 results, highlighting a significant net loss and ongoing preparations for a merger with Korsana Biosciences, while facing substantial going concern doubts.
Worse than expected
Capital raise
NASDAQ
Cyclerion Therapeutics reports reduced net losses and increased revenue, secures a new license for treatment-resistant depression, but faces substantial doubt about its ability to continue as a going concern.
Delay expected
Capital raise
NASDAQ
Cyclerion Therapeutics reports a reduced net loss and improved operating cash flow for Q2 2025, driven by an insurance recovery and new financing, but faces substantial doubt about its ability to continue as a going concern.
Worse than expected
Capital raise
NASDAQ
Cyclerion Therapeutics reports a net loss of $1.429 million for the first quarter of 2025 and discusses its strategic focus on neuropsychiatric diseases, particularly treatment-resistant depression (TRD).
Worse than expected
Capital raise
NASDAQ
Cyclerion Therapeutics' Q3 2024 results show a net loss, but include revenue from a new option agreement and reduced operating expenses.
Worse than expected
Capital raise

Annual Reports (10-K)

NASDAQ
Cyclerion Therapeutics, Inc. files an amendment to its 2025 10-K to include Part III information and new executive certifications.
Delay expected
Capital raise
NASDAQ
Cyclerion Therapeutics, Inc. filed an amendment to its 2024 Annual Report, adding a critical audit matter regarding its investment in Tisento Therapeutics Holdings Inc. while reaffirming its going concern warning.
Worse than expected
Capital raise
NASDAQ
Cyclerion Therapeutics is pivoting towards neuropsychiatric therapeutics, particularly treatment-resistant depression, while facing substantial doubt about its ability to continue as a going concern.
Worse than expected
Capital raise
NASDAQ
Cyclerion Therapeutics' 2023 10-K filing details a strategic shift away from CNS-focused sGC stimulators, the sale of key assets, and a focus on building a new portfolio.
Worse than expected
Capital raise

Insider Trading (Form 4)

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NASDAQ
Cyclerion Therapeutics announces progress on its merger with Korsana Biosciences, highlighting potential advancements in neurodegenerative disease therapies.
Capital raise
NASDAQ
Cyclerion Therapeutics announces progress on its merger with Korsana Biosciences, detailing forward-looking statements and regulatory filings.
Capital raise
NASDAQ
Cyclerion Therapeutics and Korsana Biosciences have entered into a merger agreement, aiming to combine their operations and advance drug development pipelines.
Capital raise
NASDAQ
Korsana Biosciences announces key executive and board appointments to advance its lead Alzheimer's candidate, KRSA-028, and prepare for its merger with Cyclerion Therapeutics.
NASDAQ
Peter M Hecht, a Director and 10% owner of Cyclerion Therapeutics, Inc., reported multiple transactions in common stock on July 16, 2026.
NASDAQ
Korsana Biosciences announces a reverse merger with Cyclerion Therapeutics, aiming to advance its novel Alzheimer's therapy, KRSA-028, with a $380M financing.
Capital raise

Proxy Statements (Def-14A)

NASDAQ
Cyclerion Therapeutics has filed a definitive proxy statement with the SEC.
NASDAQ
Cyclerion Therapeutics will hold its annual shareholder meeting virtually on June 16, 2025, to vote on director elections, auditor ratification, executive compensation, and other proposals.
Capital raise
NASDAQ
Cyclerion Therapeutics has filed a definitive proxy statement with the SEC, signaling upcoming shareholder actions.
NASDAQ
Cyclerion Therapeutics announces its Annual Meeting of Shareholders to be held virtually on June 14, 2024, to vote on director elections, auditor ratification, and an adjournment proposal.

Schedule 13D - Activist Investments

NASDAQ
Peter M. Hecht amends Schedule 13D, reporting a beneficial ownership of 910,240 shares of Cyclerion Therapeutics' common stock, representing 19.4% of the class.
NASDAQ
Peter M. Hecht, a significant shareholder, increased his beneficial ownership in Cyclerion Therapeutics, Inc. to 27.9% through a recent private placement of common stock.
Capital raise

Schedule 13G - Passive Investments

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NASDAQ
ADAR1 Capital Management, LLC and Daniel Schneeberger have jointly filed a Schedule 13G, reporting beneficial ownership of 7.0% of Cyclerion Therapeutics, Inc. common stock as of June 30, 2026.
NASDAQ
Balyasny Asset Management L.P. and affiliated entities have reported beneficial ownership of 317,511 shares, representing 7.33% of Cyclerion Therapeutics, Inc. common stock.
NASDAQ
FMR LLC and Abigail P. Johnson have jointly filed a Schedule 13G, reporting beneficial ownership of 15.0% of Cyclerion Therapeutics Inc.'s common stock as of April 30, 2026.
NASDAQ
J. Wood Capital Advisors LLC and Jason Wood have disclosed a 5.4% beneficial ownership stake in Cyclerion Therapeutics, Inc., holding 181,818 shares of common stock.
NASDAQ
Tyndall Capital Partners, L.P. reports a 4.8% passive ownership stake in Cyclerion Therapeutics, Inc. as of June 30, 2025.
NASDAQ
Tyndall Capital Partners, L.P. has filed an amended Schedule 13G, reporting a 5.1% beneficial ownership stake in Cyclerion Therapeutics, Inc. as of March 31, 2025.