Market Movers (8-K)
See all →Applied Therapeutics, Inc. has been acquired by Cycle Group Holdings Limited for approximately $14.3 million, with shareholders receiving cash and contingent value rights.
Capital raise
Worse than expected
Applied Therapeutics agrees to be acquired by Cycle Group Holdings for $0.088 per share in cash plus contingent value rights tied to drug development and sales milestones, alongside an $8.5 million unsecured loan.
Worse than expected
Capital raise
Applied Therapeutics, Inc. has initiated a comprehensive review of strategic alternatives to maximize shareholder value, alongside a significant workforce reduction.
Worse than expected
Delay expected
Applied Therapeutics reported a significantly reduced net loss in Q3 2025, alongside ongoing regulatory discussions for govorestat in rare diseases and a board leadership change.
Delay expected
Worse than expected
Capital raise
Applied Therapeutics, Inc. has entered into a new 'at-the-market' equity offering agreement with Cantor Fitzgerald & Co. for up to $75 million, replacing a prior agreement.
Capital raise
Applied Therapeutics, Inc. received an additional 180-day extension from Nasdaq to regain compliance with the minimum bid price requirement, resulting in a transfer to the Nasdaq Capital Market.
Better than expected
Quarterly Earnings (10-Q)
See all →Applied Therapeutics reports significant Q3 2025 net loss and ongoing liquidity concerns, alongside legal settlements and regulatory challenges for its lead drug candidates.
Delay expected
Worse than expected
Capital raise
Applied Therapeutics reports significant losses and a going concern warning following FDA rejection of its lead drug for Classic Galactosemia and ongoing litigation.
Delay expected
Worse than expected
Capital raise
Applied Therapeutics faces ongoing regulatory hurdles and leadership transitions while reporting a net loss of $21.8 million for Q1 2025.
Worse than expected
Delay expected
Capital raise
Applied Therapeutics reports a net loss of $68.6 million for Q3 2024, while highlighting progress in its clinical programs and regulatory submissions.
Worse than expected
Delay expected
Capital raise
Applied Therapeutics reports a net income of $2.9 million for the second quarter of 2024, a significant turnaround from a net loss of $29.6 million in the same period last year, driven by changes in warrant liabilities.
Worse than expected
Delay expected
Applied Therapeutics reports a net loss of $83.9 million for Q1 2024, but secures $113.8 million in net proceeds through financing activities.
Worse than expected
Delay expected
Capital raise
Annual Reports (10-K)
Applied Therapeutics receives a Complete Response Letter from the FDA for its Galactosemia drug, prompting a strategic shift towards Sorbitol Dehydrogenase (SORD) Deficiency treatment.
Delay expected
Capital raise
Worse than expected
Applied Therapeutics' 2023 10-K filing highlights advancements in their pipeline, including regulatory submissions for AT-007 and positive trial results for AT-001.
Delay expected
Capital raise
Worse than expected
Insider Trading (Form 4)
See all →A director of Applied Therapeutics, Inc. reported changes in beneficial ownership following the company's merger, converting shares and options into cash and contingent value rights.
Worse than expected
Applied Therapeutics' Chief Commercial Officer, Corwin Dale Hooks, disposed of all common stock holdings following the company's merger, receiving cash and contingent value rights.
Worse than expected
Applied Therapeutics' COO, Constantine Chinoporos, reported the disposition of all his common stock and RSUs following the company's merger with Cycle Group Holdings Limited.
Worse than expected
Applied Therapeutics director Jay S. Skyler reports zero beneficial ownership of common stock and options following the company's merger with Cycle Group Holdings Limited and AT2B, INC.
Worse than expected
Applied Therapeutics' CFO Leslie D. Funtleyder reported significant share and option dispositions following the company's merger with AT2B, INC., receiving $0.088 per share plus a contingent value right.
Worse than expected
Applied Therapeutics' Chief Medical Officer, Evan Prescott Bailey, disposed of all common stock and had out-of-the-money stock options cancelled as part of the company's merger with Cycle Group Holdings Limited.
Worse than expected
Proxy Statements (Def-14A)
DEFA14A: Applied Therapeutics Seeks Stockholder Approval for Reverse Stock Split and Executive Compensation
Applied Therapeutics is holding its annual meeting on June 9, 2025, seeking stockholder votes on director election, auditor ratification, executive compensation, and a reverse stock split.
Applied Therapeutics is asking stockholders to approve a reverse stock split at its annual meeting on June 9, 2025, to regain compliance with Nasdaq listing requirements.
Capital raise
Worse than expected
Applied Therapeutics, Inc. has filed a definitive proxy statement with the U.S. Securities and Exchange Commission.
Applied Therapeutics is holding its annual stockholder meeting on June 6, 2024, to vote on director elections, auditor ratification, an increase in authorized shares, and other matters.
Capital raise
Schedule 13G - Passive Investments
See all →Propel Bio Management, Leen Kawas, and Richard Kayne, along with Propel Bio Partners, have filed an amendment to their Schedule 13G, reporting a 4.17% beneficial ownership in Applied Therapeutics, Inc.
Worse than expected
Alexandria Real Estate Equities and its subsidiaries have updated their beneficial ownership in Applied Therapeutics, Inc., reporting a combined stake primarily through warrants.
T. Rowe Price Investment Management, Inc. has disclosed a beneficial ownership of 14.9% in Applied Therapeutics Inc., holding 21,403,300 common shares as of September 30, 2025.
SCHEDULE 13G/A: T. Rowe Price Boosts Stake in Applied Therapeutics to 13.2%
T. Rowe Price Investment Management, Inc. has reported a significant beneficial ownership stake of 13.2% in Applied Therapeutics Inc., holding 18,683,990 shares.
The Vanguard Group has filed an amended Schedule 13G, revealing a 3.34% beneficial ownership stake in Applied Therapeutics Inc. as of June 30, 2025.
SCHEDULE 13G/A: BlackRock Discloses 3.7% Passive Stake in Applied Therapeutics
BlackRock, Inc. has filed an amended Schedule 13G, reporting a 3.7% beneficial ownership stake in Applied Therapeutics Inc., held as a passive investment.