Form 4: Spyre Therapeutics Executive Sells Shares

Sentiment:

Insider Transaction (Form 4)


Heidy King-Jones, See Remarks of Spyre Therapeutics, Inc., sold 28,933 shares of common stock on October 1, 2026.

Summary

  • Option exercise/conversion: acquired 28,933 Common Stock at $14.50 ($419,528) on October 1, 2026; holds 31,778 after (Direct).
  • Open-market sale: disposed of 400 Common Stock at $89.24 ($35,696) on October 1, 2026; holds 31,378 after (Direct).
  • Open-market sale: disposed of 16,605 Common Stock at $90.35 ($1,500,262) on October 1, 2026; holds 14,773 after (Direct).
  • Open-market sale: disposed of 7,228 Common Stock at $91.35 ($660,278) on October 1, 2026; holds 7,545 after (Direct).
  • Open-market sale: disposed of 2,100 Common Stock at $92.70 ($194,670) on October 1, 2026; holds 5,445 after (Direct).
  • Open-market sale: disposed of 2,600 Common Stock at $93.46 ($242,996) on October 1, 2026; holds 2,845 after (Direct).
  • Option exercise/conversion: disposed of 28,933 Stock Option (Right to Buy) on October 1, 2026; holds 482,478 after (Direct).

Sentiment

Score: 4

Explanation: StockSavvy.ai views this as a mildly negative but low-conviction signal: an insider sold $2,633,902 of stock under a pre-arranged Rule 10b5-1 plan, which is typically routine.

Insider Transactions

Heidy King-Jones — Officer (See Remarks)

Transaction made under a Rule 10b5-1 trading plan.

DateTransactionSecuritySharesPriceValueHeld After
2026-10-01Option exercise/conversionCommon Stock28,933$15$419.5K31,778
2026-10-01Open-market saleCommon Stock400$89$35.7K31,378
2026-10-01Open-market saleCommon Stock16,605$90$1.5M14,773
2026-10-01Open-market saleCommon Stock7,228$91$660.3K7,545
2026-10-01Open-market saleCommon Stock2,100$93$194.7K5,445
2026-10-01Open-market saleCommon Stock2,600$93$243.0K2,845
2026-10-01Option exercise/conversionStock Option (Right to Buy)28,933——482,478

Key Dates

DateDescription
2026-10-01Option exercise/conversion (28,933 shares)
2026-10-01Open-market sale (400 shares)
2026-10-01Open-market sale (16,605 shares)
2026-10-01Open-market sale (7,228 shares)
2026-10-01Open-market sale (2,100 shares)
2026-10-01Open-market sale (2,600 shares)
2026-10-01Option exercise/conversion (28,933 shares)

Keywords

insider transaction, Form 4, SYRE, Spyre Therapeutics, Inc., bearish, Heidy King-Jones

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